For a Few Dollars More follows two rival bounty hunters—the mysterious "Man with No Name" (Manco) and the vengeful Colonel Douglas Mortimer—who reluctantly team up to track down El Indio, a ruthless and sadistic bandit leader with a massive price on his head. Each man has his own hidden motive: Manco wants the lucrative reward money, while Mortimer seeks personal revenge for the tragic death of his sister. After infiltrating Indio's gang, surviving a brutal betrayal, and playing the bandits against each other, the two bounty hunters corner the outlaws in a deadly final showdown. Mortimer kills Indio in a dramatic duel, avenging his family, and allows Manco to collect all the bounty money as they part ways with mutual respect.